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Evolution and Development of Neural Circuits


Book Series:  A Cold Spring Harbor Perspectives in Biology Collection
Subject Area(s):  Developmental BiologyNeurobiology

Edited by Laura C. Andreae, King's College London; Justus M. Kebschull,  Johns Hopkins University; Anthony M. Zador, Cold Spring Harbor Laboratory

Download a Free Excerpt from Evolution and Development of Neural Circuits:

Preface
Neuronal Circuit Evolution: From Development to Structure and Adaptive Significance
Index


Due November 2025 • 248 pages, illustrated (49 color and 2 B&W), index
Hardcover •
ISBN  978-1-621824-84-8

  •     Description    
  •     Contents    

Description

This outstanding volume on the evolution and development of neural circuits explores how brains are built, diversified, and adapted in a variety of species, integrating perspectives from evolutionary biology, developmental neuroscience, and systems neurobiology. Recent advances in molecular genetics, neuroanatomy, physiology, imaging, and computational modeling have enabled unprecedented insights into the mechanisms that shape neural circuits.

Key themes explored in the book include:

  • The evolutionary divergence and convergence of circuit motifs
  • The conserved molecular and developmental building blocks that underlie connectivity
  • The rules and mechanisms that sculpt neural systems

Chapters cover topics ranging from retinal mapping and interneuron diversity to thalamocortical connectivity, prefrontal circuit maturation, and the computational modeling of both normal and abnormal circuit development. Collectively, these essays reveal how molecular signaling, cellular variability, and theoretical principles converge to shape the formation and function of circuits across vertebrate and invertebrate brains. By combining evolutionary and developmental frameworks, this volume offers both specialists and newcomers a broad and integrative view of how neural circuits emerge and operate, providing a resource for neuroscientists at every level of training who seek to understand the principles of brain design. of brain design.

Contents

Preface
Neuronal Circuit Evolution: From Development to Structure and Adaptive Significance
Nikolaos Konstantinides and Claude Desplan
Cell Adhesion Molecule Signaling at the Synapse: Beyond the Scaffold
Ben Verpoort and Joris de Wit
Development of Prefrontal Circuits and Cognitive Abilitie
Jastyn A. Pöpplau and Ileana L. Hanganu-Opatz
Development and Evolution of Thalamocortical Connectivity
Zoltán Molnár and Kenneth Y. Kwan
Variability in Neural Circuit Formation
Kevin J. Mitchell
Bringing Chandelier Cells Out of the Shadows: Exploring the Development
of a Unique Neuron Type in the Brain
Clara Lenherr, Guilherme Neves, Marcio Guiomar de Oliveira, and Juan Burrone
Characterizing Large-Scale Human Circuit Development with In Vivo Neuroimaging
Tomoki Arichi
Modeling Normal and Abnormal Circuit Development with Recurrent Neural Networks
Daniel Zavitz, ShiNung Ching, and Geoffrey Goodhill
Reimagining Cortical Connectivity by Deconstructing Its Molecular Logic
into Building Blocks
Xiaoyin Chen
The Unusual Effectiveness of Evolution in Systems Neuroscience
Arkarup Banerjee, Steven M. Phelps, and Justus M. Kebschull
Modeling the Emergence of Circuit Organization and Function during Development
Shreya Lakhera, Elizabeth Herbert, and Julijana Gjorgjieva
Mapping the Retina onto the Brain
Daniel Kerschensteiner and Marla B. Feller
Interneuron Diversity: How Form Becomes Function
Natalia V. De Marco García and Gord Fishell
Convergent Circuit Computation for Categorization in the Brains
of Primates and Songbirds
Andreas Nieder
Index