Glia, Second Edition

Click to Enlarge				Glia, Second Edition Book Series: A Cold Spring Harbor Perspectives in Biology Collection Subject Area(s): Neurobiology; Cytology Edited by Beth Stevens, Boston Children's Hospital; Kelly R. Monk, OHSU -Vollum Institute; Marc R. Freeman, OHSU -Vollum Institute

				© 2025 • 686 pages, illustrated (94 color), index Hardcover • $79 ISBN 978-1-621824-64-0

Description Contents Description Glia represent the majority of cells in the nervous system. Originally believed to be passive cells that support the neurons that transmit electrical signals, glial cells are now known to play a far more active part in neural development and function than previously appreciated. Written and edited by experts in the field, this new collection from Cold Spring Harbor Perspectives in Biology examines recent progress in our understanding of the major classes of glial cells—astrocytes, oligodendrocytes, Schwann cells, and microglia. The contributors review how technical advances and the use of worm, fly, and fish model systems are providing fascinating insights into the roles of glia in normal physiology and disease. They discuss how glia control synapse formation and plasticity, regulate blood flow, and organize axonal domains. They describe how glia are formed and generated from precursor cells during development. Other chapters tackle the roles of glial cells in myelination, connections with the lymphatic system, and neuroimmune interactions. The authors also discuss the functions of glia in tissue repair and regeneration, as well as disease processes such as glioma, demyelinating diseases, and neurodegenerative conditions. This volume is therefore a valuable reference for neuroscientists and biologists wishing to understand how these pathologies arise. Contents Preface Non-Mammalian Models for Studying Glial Biology Glia Development and Function in the Nematode Caenorhabditis elegans Aakanksha Singhvi, Shai Shaham, and Georgia Rapti Glial Regulation of Circuit Wiring, Firing, and Expiring in the Drosophila Central Nervous System Jaeda Coutinho-Budd, Marc R. Freeman, and Sarah Ackerman Glia as Functional Barriers and Signaling Intermediaries Vilaiwan M. Fernandes, Vanessa Auld, and Christian Klämbt Glial Cell Development and Function in the Zebrafish Central Nervous System Tim Czopka, Kelly Monk, and Francesca Peri Astrocytes Generation of Mammalian Astrocyte Functional Heterogeneity Theresa Bartels, David H. Rowitch, Omer Ali Bayraktar Astrocyte Regulation of Synapse Formation, Maturation, and Elimination Won-Suk Chung, Katherine T. Baldwin, and Nicola J. Allen Astrocyte Calcium Signaling Misha B. Ahrens, Baljit S. Khakh, and Kira E. Poskanzer Astrocyte Regulation of Cerebral Blood Flow in Health and Disease Anusha Mishra, Grant R. Gordon, Brian A. MacVicar, and Eric A. Newman The Astrocyte: Metabolic Hub of the Brain L. Felipe Barros, Stefanie Schirmeier, and Bruno Weber Reactive Astrocytes and Emerging Roles in Central Nervous System (CNS) Disorders Shane A. Liddelow, Michelle L. Olsen, and Michael V. Sofroniew Oligodendrocytes and Myelination Features, Fates, and Functions of Oligodendrocyte Precursor Cells Robert A. Hill, Akiko Nishiyama, and Ethan G. Hughes Regulators of Oligodendrocyte Differentiation Ben Emery and Teresa L. Wood Oligodendrocytes: Myelination, Plasticity, and Axonal Support Mikael Simons, Erin M. Gibson, and Klaus-Armin Nave Schwann Cells Schwann Cell Development and Myelination James Salzer, M. Laura Feltri, and Claire Jacob The Nodes of Ranvier: Mechanisms of Assembly and Maintenance Matthew N. Rasband and Elior Peles Perisynaptic Schwann Cells: Guardians of Neuromuscular Junction Integrity and Function in Health and Disease Thomas W. Gould, Chien-Ping Ko, Hugh Willison, and Richard Robitaille Schwann Cells as Orchestrators of Nerve Repair: Implications for Tissue Regeneration and Pathologies Ruth M. Stassart, Jose A. Gomez-Sanchez, and Alison C. Lloyd Microglia Microglial in Health and Diseases: Integrative Hubs of the Central Nervous System (CNS) Amanda Sierra, Veronique E. Miron, Rosa C. Paolicelli, and Richard M. Ransohoff Microglia function in central nervous system development & plasticity Dorothy P. Schafer, Beth Stevens, Mariko L. Bennett, and F. Chris Bennett Neuroimmune Interactions and Glia at the Borders of Neural Tissues The Blood-Brain Barrier: Composition, Properties, and Roles in Brain Health Baptiste Lacoste, Alexandre Prat, Moises Freitas-Andrade, and Chenghua Gu Satellite Glial Cells: No Longer the Most Overlooked Glia Susan J. Birren, Lisa V. Goodrich, and Rosalind A. Segal Enteric Glia Meenakshi Rao and Brian D. Gulbransen Glia at Transition Zones Sarah Kucenas, Pernelle Pulh, Piotr Topilko, and Cody J. Smith Cellular Contributions to Glymphatic and Lymphatic Waste Clearance in the Brain Leon Smyth, Natalie Beschorner, Maiken Nedergaard, and Jonathan Kipnis Disease and Repair Remyelination in the Central Nervous System Robin J.M. Franklin, Benedetta Bodini, and Steven A. Goldman Glial Malignancies Suzanne J. Baker, Hui Zong, and Michelle Monje Glia in Neurodegenerative Disease Gerard Crowley, David Attwell, Hemali Phatnani, Harald Sontheimer, and Soyon Hong Multiple Sclerosis and Other Acquired Demyelinating Diseases of the Central Nervous System Michael D. Kornberg and Peter A. Calabresi Glial Origins of Inherited White Matter Disorders Anjana Sevagamoorthy, Adeline Vanderver, Jamie L. Fraser, and Jennifer Orthmann-Murphy Peripheral Nervous System (PNS) Myelin Diseases Steven S. Scherer and John Svaren Index

Glia, Second Edition

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